| 名称 |
anti- ACADVL antibody |
| 来源 |
Rabbit |
| 应用 |
ELISA, WB, IHC |
| 反应 |
Human, Mouse, Rat |
| 稀释范围 |
WB: 1:200-1:2000; IHC: 1:20-1:200 |
| 克隆 |
polyclonal |
| 蛋白号 |
P49748 |
| 分子质量 |
48 kDa,68-73 kDa |
| 纯化 |
Immunogen affinity purified |
| 纯度 |
≥95% as determined by SDS-PAGE |
| 状态 |
liquid |
| 免疫原 |
acyl-Coenzyme A dehydrogenase, very long chain |
| 亚型 |
IgG |
| 存储 |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| 别名 |
ACAD6, ACADVL, LCACD, VLCAD |
| 背景介绍 |
Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71-kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa(tryptic digest) polypeptide(PMID:9461620). Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). It has 2 isoforms(70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide. |
