anti- MDM2 antibody

产品编号 HYab17689
产品分类 一抗
品牌 华韵生物
规格 50ug 100µg
应用 ELISA, IHC, WB, IF
反应 Human, Mouse, Rat
品牌 货号 纯度 规格 目录价(CNY) 会员价(CNY) 数量 购物车
华韵生物 HYab17689-50ug 50ug ¥2250.00
华韵生物 HYab17689-100µg 100µg ¥3750.00
查询MSDS 大包装询盘
名称 anti- MDM2 antibody
来源 Rabbit
应用 ELISA, IHC, WB, IF
反应 Human, Mouse, Rat
稀释范围 WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
克隆 polyclonal
蛋白号 Q00987
分子质量 50 kDa
纯化 Immunogen affinity purified
纯度 ≥95% as determined by SDS-PAGE
状态 liquid
免疫原 Mdm2 p53 binding protein homolog ( Mouse )
亚型 IgG
存储 PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
别名 ACTFS
背景介绍 This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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